International Workshop: Synchrotron and Neutron Scattering in Biomaterials and Soft Matter

26 Oct 2016, 09:05 → 28 Oct 2016, 15:30 Europe/Stockholm

Main Aula (Health and Society, Malmö University)

    

 

Synchrotron and Neutron Scattering in Biomaterials and Soft Matter

The aim of the workshop is to gather a community of current and future users of neutron scattering within the cross-interdisciplinary areas of biology and soft matter. The idea is to show the mutual benefit when traditional methodologies from soft matter sciences are brought together and applied to biological systems.

Besides basic science, we aim to demonstrate the capability of neutron and synchrotron scattering on biomedical and technological applications including:

• Formulation of biologics
• Drug design
• Pharmaceuticals
• Implants

This meeting further aims to gather experts across disciplines so as to strengthen and develop the expertise in scattering techniques within the Nordic community.

The workshop is aimed at both industry and academia. There will be four main sessions focusing on:

• Biology
• Interfaces
• Solution
• Industrial applications

Each session will end with a group discussion on what are the conditions required to increase and strengthen the user community of MAX IV and ESS.

Follow this link for directions from Traingle train station, south.

Directions/Map https://www.google.com/maps/dir/Malm%C3%B6+Triangeln+station,+Sweden/Jan+Waldenstr%C3%B6ms+gata+25,+214+21+Malm%C3%B6,+Sweden/@55.5907366,12.9988832,17z/data=!4m13!4m12!1m5!1m1!1s0x4653a15a9c7330c3:0x67d7e4b13c27de29!2m2!1d13.0018855!2d55.5919717!1m5!1m1!1s0x4653a14563447afd:0x1651c6e621c22661!2m2!1d12.9995942!2d55.5895023

Flyer Flyer_Workshop_Synchrotron_and_Neutron_Scattering_October.pdf

Program Final_Program_Workshop_2016.pdf

Wednesday 26 October

12:05 Registration

Biology

Relevant biological applications where neutron and x-ray scattering are relevant

1 Neutron and x-ray scattering approaches for interdisciplinary structural biology

Speaker: Prof. Trevor Forsyth (Keele University)

2 Synchrotron radiation aids structure based inhibitor development - towards novel antibiotics

Speaker: Dr ROBERT SCHNELL (KAROLINSKA INSTITUTET, DEPT. OF MEDICAL BIOCHEMISTRY AND BIOPHYSICS)

3 Probing the structure and dynamics of HSA using neutron scattering

Speaker: Dr Melissa Sharp (European Spallation Source)

4 Metabolic plasticity as mediated by the dhurrin metabolon

Speaker: Prof. Birger Lindberg Moller (University of Copenhagen)

15:10 COFFEE BREAK

5 Synchrotron imaging of soft tissue biopsies

Speaker: Dr Martin Bech (Lund University)

6 Lipoprotein structure dependency on lipid cargo and exchange dynamics - Implications for atherosclerosis development

Speaker: Dr Selma Maric (Malmö University)

7 Structural and dynamics studies of a truncated variant of CI repressor from bacteriophage TP901-1

Speakers: Dr Kim Krighaar Rasmussen (University of Copenhagen), Mr Kim Krighaar Rasmussen (University of Copenhagen)

PANEL DEBATE, BIOLOGY

Thursday 27 October

8 Model membranes, living organisms and lateral membrane organization

Speaker: Dr John Katsaras (Oak Ridge National Laboratory)

Solution

Biomolecules and biomolecular aggregates in solution

9 A small-angle view on macromolecular self-assembly: from supramolecular interactions to supramolecular structures

Speaker: Prof. Ilja Voets (University of Technology of Eindhoven)

10 Citrem-phospholipid lamellar and non-lamellar liquid crystalline nano-assemblies for immune-safe drug delivery

Speaker: Mrs Intan Diana Mat Azmi (PhD student)

10:30 COFFEE BREAK and Poster Session

11 Refolding of SDS-unfolded proteins by non-ionic surfactants

Speaker: Prof. Jan Skov Pedersen (Århus University)

12 High-resolution structure, interactions, and dynamics of self-assembled biomolecular complexes

Speaker: Prof. Uri Raviv (The Hebrew University of Jerusalem)

13 SANS study of the self-aggregation of alkylglycoside surfactants with oligomeric head-groups

Speaker: Dr Federica Sebastiani (CR Competence AB & Department of Physical Chemistry, University of Lund)

12:20 Lunch

Industrial Applications

Relevant industrial applications where neutron and X-ray scattering are relevant to advance the field

14 Small-angle x-ray and neutron scattering – complementary approaches for understanding colloid and interface behavior of systems relevant for technical applications of enzymes

Speaker: Dr Thomas H Callisen (Novozymes R&D)

15 Drug delivery applications of self-assembling lipid formulations

Speaker: Dr Justas Barauskas (Camurus AB)

16 Introducing new industrial users to large scale X-ray and neutron facilities

Speaker: Soren Midtgaard (University of Copenhagen)

14:40 COFFEE BREAK and Poster Session

17 When thrown into the wonderful mix of constraints and desires, there is a product and a customer...

Speaker: Mrs Anna Stenstam (CR Competence AB)

18 Neutrons and Industry: How the ISIS Neutron Scattering Source Interacts with Industry

Speaker: Dr Sarah Rogers (ISIS, STFC)

19 Realizing the potential of research infrastructures

Speaker: Dr Tomas Lundqvist (MAX IV Laboratory)

PANEL DEBATE, INDUSTRY

20 Buss transport

19:00 Dinner

Friday 28 October

Interfaces

Relevant cases at interfaces

21 Neutron Reflection

Speaker: Dr Bob Thomas (University of Oxford)

22 Molecular dynamics simulations and neutron reflectivity as an effective approach to characterize biological membranes and related macromolecular assemblies

Speaker: Dr Carmen Domene (King's College London)

23 Molecular transport in lipid membranes: lipid exchange and translocation processes investigated by neutron scattering

Speaker: Dr Yuri Gerelli (Institut Laue - Langevin)

10:30 COFFEE BREAK

24 Studying soft matter surfaces and interfaces with in-situ and in-operando x-ray and neutron scattering

Speaker: Prof. Peter Müller-Buschbum (TU München)

25 Can neutron reflectometry offer structural and compositional information about native supported cell membranes and biological nanoparticles?

Speaker: Prof. Fredrik Höök (Chalmers)

26 Multi-modal and high-resolution investigation of biodegradable Mg implants in bone

Speaker: Mrs Silvia Galli (Department of Prosthodontics, Faculty of Odontology, Malmö University)

12:20 Lunch and bus transport

13:30 Excursion to MAX IV/ESS