Dr
Brian Metscher
(University of Vienna)
Zoology
oral
3D imaging has become a familiar player in developmental and comparative biology, offering ever more realistic views of the native structures of organisms and materials. For morphology-based studies of development and evolution, X-ray microtomography (microCT) is the most suitable method to visualize 3D micromorphology in whole embryos and other intact samples. Contrast-enhanced microCT can...
Dr
Liisa Porra
(University of Helsinki, Finland)
Medicine, pre-clinical studies
oral
**Rationale:** Despite the importance of dynamic changes in the regional distributions of gas and blood during the breathing cycle for lung function in the mechanically ventilated patient, no quantitative data on such cyclic changes is currently available.
**Methods:** We used a novel gated synchrotron CT-imaging with K-edge subtraction technique to quantitatively image regional lung gas...
Dr
Tomasz W. Wysokinski
(Canadian Light Source)
Small animal imaging and therapy
oral
Synchrotrons provide users with unique imagining and therapeutic methods. They provide very high flux, with flat energy spectrum and quasi-coherent beam. At the same time synchrotrons are very different from clinical machines: beam is parallel and has limited size, its position is fixed and sample, together with the required live support and diagnostic equipment, has to be rotated or...
Prof.
Jukka Jernvall
(University of Helsinki)
Developmental biology & Palaeontology
oral
Teeth are three-dimensional consisting of highly mineralized tissues. Both the formation of tooth shape during development and the structural details of mature dental tissues are active topics of research. We have used phase-contrast holotomography synchrotron imaging to study mineralized dental ultrastructure with voxel resolutions down to 25 nanometres. The resulting details uncovered...
Marianne Liebi
Spectroscopy, soft X-rays and scattering imaging
oral
Small-angle X-ray scattering (SAXS) probes structures in the size-range of one to several hundred nanometers. Raster scanning a sample through a focused X-ray beam allows to record SAXS pattern spatially resolved. The information extracted from each scattering pattern can be used to construct images with different contrasts. Bragg peaks arising from characteristic distances in the sample, such...
Dr
Corfe Ian
(Institute of Biotechnology, University of Helsinki)
Developmental biology & Palaeontology
oral
Palaeontological applications of synchrotron techniques such as tomography and spectroscopy have offered a new dimension to palaeobiological studies, revealing what extinct animals ate, the long believed unknowable colour of ancient animals from insects to dinosaurs, and the life histories of animals from the earliest tetrapods to the first humans. Despite recent discoveries and analyses...
Dr
Kevin Mader
(4Quant Ltd.)
Sample preparation and Image analysis
oral
The diagnosis and treatment of lung cancer has been drastically improved by new imaging methods which generate large number of images where single spots can drastically influence the diagnosis and treatment. For physicians this means a long time must be spent carefully reading images. 4Quant (an ETH Spinoff) together with the University Hospital Basel have demonstrated the potential to...
